Browsing by Author "Quispe, C."

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    ReviewPublicationOpen Access
    Glycyrrhiza genus: Enlightening phytochemical components for pharmacological and health-promoting abilities
    (Hindawi Limited, 2021-07-26) Sharifi-Rad, J.; Quispe, C.; Herrera-Bravo, J.; Belén, L. H.; Kaur, R.; Kregiel, D.; Uprety, Y.; Beyatli, A.; Yeskaliyeva, B.; Kırkın, Celale; Özçelik, B.; Sen, S.; Acharya, K.; Sharopov, F.; Cruz-Martins, N.; Kumar, M.; Razis, A. F. A.; Sunusi, U.; Kamal, R. M.; Shaheen, S.; Suleria, H. A. R.; Gastronomy and Culinary Arts; KIRKIN, Celale
    The Glycyrrhiza genus, generally well-known as licorice, is broadly used for food and medicinal purposes around the globe. The genus encompasses a rich pool of bioactive molecules including triterpene saponins (e.g., glycyrrhizin) and flavonoids (e.g., liquiritigenin, liquiritin). This genus is being increasingly exploited for its biological effects such as antioxidant, antibacterial, antifungal, anti-inflammatory, antiproliferative, and cytotoxic activities. The species Glycyrrhiza glabra L. and the compound glycyrrhizin (glycyrrhizic acid) have been studied immensely for their effect on humans. The efficacy of the compound has been reported to be significantly higher on viral hepatitis and immune deficiency syndrome. This review provides up-to-date data on the most widely investigated Glycyrrhiza species for food and medicinal purposes, with special emphasis on secondary metabolites' composition and bioactive effects.
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    ReviewPublicationOpen Access
    Paving plant-food-derived bioactives as effective therapeutic agents in autism spectrum disorder
    (Hindawi Limited, 2021-08-23) Cruz-Martins, N.; Quispe, C.; Kirkin, C.; Şenol, E.; Zuluğ, Aslı; Özçelik, B.; Ademiluyi, A. O.; Oyeniran, O. H.; Semwal, P.; Kumar, M.; Sharopov, F.; López, V.; Gastronomy and Culinary Arts; ZULUĞ, Aslı
    Autism spectrum disorder (ASD) is a neurodevelopmental disorder, where social and communication deficits and repetitive behaviors are present. Plant-derived bioactives have shown promising results in the treatment of autism. In this sense, this review is aimed at providing a careful view on the use of plant-derived bioactive molecules for the treatment of autism. Among the plethora of bioactives, curcumin, luteolin, and resveratrol have revealed excellent neuroprotective effects and can be effectively used in the treatment of neuropsychological disorders. However, the number of clinical trials is limited, and none of them have been approved for the treatment of autism or autism-related disorder. Further clinical studies are needed to effectively assess the real potential of such bioactive molecules.