Browsing by Author "Çakmak, O."

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    Conference paperPublicationMetadata only
    MEMS based blood plasma viscosity sensor without electrical connections
    (IEEE, 2013) Çakmak, O.; Ermek, E.; Urey, H.; Yaralıoğlu, Göksen Göksenin; Kılınç, N.; Electrical & Electronics Engineering; YARALIOĞLU, Göksen Göksenin
    A MEMS based viscometer is reported. The device has a disposable cartridge and a reader. The cartridge contains microfluidic channels and a MEMS cantilever sensor. The reader contains the actuator and the readout optics and electronics. A unique feature of the system is that both the actuation and the sensing are remote; therefore, no electrical connections are required between the reader and the cartridge. The reported sensor is capable of measuring viscosity with better than 0.01 cP resolution in a range of 0.8-14.1 cP, with less than 50 μl sample requirement. This range and sensitivity are sufficient for blood plasma viscosity measurements, which are in between 1.1-1.3 cP for healthy individuals and can be elevated to 3cP in certain diseases[1].
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    Conference paperPublicationOpen Access
    Microcantilever based LoC system for coagulation measurements
    (Chemical and Biological Microsystems Society, 2014) Çakmak, O.; Ermek, E.; Kılınç, N.; Barış, I.; Kavaklı, I. H.; Yaralıoğlu, Göksen Göksenin; Urey, H.; Electrical & Electronics Engineering; YARALIOĞLU, Göksen Göksenin
    In this paper, a microcantilever-based system enabling multiple coagulation tests on the same disposable cartridge is demonstrated. The system consists of independent cartridge and reader unit. The actuation of the nickel cantilevers is conducted remotely with an external electro-coil and remote optical read-out is utilized for sensing. Both Prothrombin Time (PT) and activated Partial Thromboplastin Time (aPTT) tests can be conducted on the same cartridge. The system’s repeatability and accuracy is investigated with standard control plasma samples. The results are concordant with the manufacturer’s datasheet. The architecture of the system and the repeatable results makes the system suitable for Point-of-Care applications.