A column generation-based approach for the adaptive stochastic blood donation tailoring problem
Type :
Article
Publication Status :
Published online
Access :
restrictedAccess
Abstract
Managing blood donations is a challenging problem due to the perishability of blood, limited donor pool, deferral time restrictions, and demand uncertainty. The problem addressed here combines two important aspects of blood supply chain management: the inventory control of blood products and the donation schedule. We propose a stochastic scenario-based reformulation of the blood donation management problem that adopts multicomponent apheresis and utilises donor pool segmentation into here-and-now and wait-and-see donors. We propose a flexible donation scheme that is resilient against demand uncertainty. This scheme enables more flexible donation schedules because wait-and-see donors may adjust their donation schedules according to the realised values of demand over time. We propose a column generation-based approach to solve the associated multi-stage stochastic donation tailoring problem. The numerical results show the effectiveness of the proposed optimisation model, which provides solutions with less than a 7% optimality gap on average with respect to a lower bound. It also improves the operational cost of the standard donation scheme that does not use wait-and-see donors by more than 18% on average. Utilising multicomponent apheresis and flexible wait-and-see donations are suggested for donation organisations because they yield significant cost reductions and resilient donation schedules.
Source :
International Journal of Production Research
Date :
2023
Publisher :
Taylor & Francis
URI
http://hdl.handle.net/10679/9103https://www.tandfonline.com/doi/full/10.1080/00207543.2023.2288866?scroll=top&needAccess=true
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