Browsing by Subject "Micro-C"
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A comparison of topologically associating domain callers over mammals at high resolution
(BioMed Central Ltd, 2022-04-12)Background: Topologically associating domains (TADs) are locally highly-interacting genome regions, which also play a critical role in regulating gene expression in the cell. TADs have been first identified while investigating ... -
ProbC: joint modeling of epigenome and transcriptome effects in 3D genome
(BioMed Central Ltd, 2022-12)Background: Hi-C and its high nucleosome resolution variant Micro-C provide a window into the spatial packing of a genome in 3D within the cell. Even though both techniques do not directly depend on the binding of specific ...
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