Browsing by Subject "Epigenetics"
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Hi–C interaction graph analysis reveals the impact of histone modifications in chromatin shape
(Springer, 2021-07-17)Chromosome conformation capture experiments such as Hi–C map the three-dimensional spatial organization of genomes in a genome-wide scale. Even though Hi–C interactions are not biased towards any of the histone modifications, ... -
Joint modeling of histone modifications in 3D genome shape through Hi-C interaction graph
(Springer, 2021)Chromosome conformation capture experiments such as Hi-C are used to map the three-dimensional spatial organization of genomes. Even though Hi-C interactions are not biased towards any of the histone modifications, previous ... -
ProbC: joint modeling of epigenome and transcriptome effects in 3D genome
(BioMed Central Ltd, 2022-12)Background: Hi-C and its high nucleosome resolution variant Micro-C provide a window into the spatial packing of a genome in 3D within the cell. Even though both techniques do not directly depend on the binding of specific ...
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