Cakmak, O.Kılınç, N.Ermek, E.Mostafazadeh, A.Elbuken, Ç.Yaralıoğlu, Göksen GökseninUrey, H.2016-02-162016-02-162014978-1-4799-3509-31084-6999http://hdl.handle.net/10679/2530https://doi.org/10.1109/MEMSYS.2014.6765643Due to copyright restrictions, the access to the full text of this article is only available via subscription.This paper reports a MEMS-based sensor array enabling multiple clot-time tests in one disposable microfluidic cartridge using plasma. The versatile LoC (Lab-on-Chip) platform technology is demonstrated here for real-time coagulation tests (activated Partial Thrompoblastin Time (aPTT) and Prothrombin Time (PT)). The system has a reader unit and a disposable cartridge. The reader has no electrical connections to the cartridge, which consists of multiple microfluidic channels and MEMS microcantilevers placed in each channel. Microcantilevers are made of electro-plated nickel and actuated remotely using an external electro-coil. The read-out is also conducted remotely by a laser and the phase of the MEMS oscillator is monitored real-time. The system is capable of monitoring coagulation time with a precision estimated at 0.1sec.enginfo:eu-repo/semantics/restrictedAccessConference paper33033300035221750008610.1109/MEMSYS.2014.6765643CoagulationLab-on-a-chipMicrofluidicsMicrosensors2-s2.0-84899010391