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dc.contributor.authorCarl, C.
dc.contributor.authorAçık, Alper
dc.contributor.authorKönig, P.
dc.contributor.authorEngel, A. K..
dc.contributor.authorHipp, J. F.
dc.date.accessioned2014-04-26T07:43:07Z
dc.date.available2014-04-26T07:43:07Z
dc.date.issued16.01.2012
dc.identifier.issn1053-8119
dc.identifier.urihttp://hdl.handle.net/10679/332
dc.identifier.urihttp://www.sciencedirect.com/science/article/pii/S1053811911010664
dc.description.abstractElectro- and magnetoencephalography (EEG/MEG) are the means to investigate the dynamics of neuronal activity non-invasively in the human brain. However, both EEG and MEG are also sensitive to non-neural sources, which can severely complicate the interpretation. The saccadic spike potential (SP) at saccade onset has been identified as a particularly problematic artifact in EEG because it closely resembles synchronous neuronal gamma band activity. While the SP and its confounding effects on EEG have been thoroughly characterized, the corresponding artifact in MEG, the saccadic spike field (SF), has not been investigated. Here we provide a detailed characterization of the SF. We simultaneously recorded MEG, EEG, gaze position and electrooculogram (EOG). We compared the SF in MEG for different saccade sizes and directions and contrasted it with the well-known SP in EEG. Our results reveal a saccade amplitude and direction dependent, lateralized saccadic spike artifact, which was most prominent in the gamma frequency range. The SF was strongest at frontal and temporal sensors but unlike the SP in EEG did not contaminate parietal sensors. Furthermore, we observed that the source configurations of the SF were comparable for regular and miniature saccades. Using distributed source analysis we identified the sources of the SF in the extraocular muscles. In summary, our results show that the SF in MEG closely resembles neuronal activity in frontal and temporal sensors. Our detailed characterization of the SF constitutes a solid basis for assessing possible saccadic spike related contamination in MEG experiments.en_US
dc.description.sponsorshipthe European Union ; the German Federal Ministry of Education and Research
dc.language.isoengen_US
dc.publisherElsevieren_US
dc.relationinfo:eu-repo/grantAgreement/EU/FP7/270212
dc.relationinfo:eu-repo/grantAgreement/EU/FP7/270212en_US
dc.relation.ispartofNeuroImage
dc.rightsopenAccess
dc.titleThe saccadic spike artifact in MEGen_US
dc.typeArticleen_US
dc.description.versionpublisher version
dc.peerreviewedyesen_US
dc.publicationstatuspublished
dc.identifier.volume59
dc.identifier.issue2
dc.identifier.startpage1657
dc.identifier.endpage1667
dc.identifier.wosWOS:000298210600088
dc.identifier.doi10.1016/j.neuroimage.2011.09.020
dc.subject.keywordsMEGen_US
dc.subject.keywordsEEGen_US
dc.subject.keywordsSaccadic spike potentialen_US
dc.subject.keywordsSaccadic spike fielden_US
dc.subject.keywordsExtraocular musclesen_US
dc.subject.keywordsGamma banden_US


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